Adam Devine

Sam-I-Am (voice)

Michael Douglas

Guy-Am-I (voice)

Ilana Glazer

Eb (voice)

Diane Keaton

Michellee (voice)

Keegan-Michael Key

Narrator (voice)

Jillian Bell

Gluntz / Hayzel (voice)

Dee Bradley Baker

Chickeraffe (voice) / Dolphacuda (voice) / Camelope (voice)

David Kaye

Dad Fish/Crony 1 (voice) / Conductor (voice) / Joaquin Furmano / Smoothie Salesman / Cabbie Left (voice) / Father (voice) / Guard 2 (voice) / PA Announcer (voice) / Grizzled Patrol Zook (voice) / Announcer (voice) / Zook Guard / Joaquin Furmano (voice) / Executive (voice) / Yook 2 (voice) / Taxi Driver (voice) / Joaquin Furmano (voice) / Patrol Zook 2 (voice)

Fred Tatasciore

Townsperson 1 (voice) / Patrol Zook / Thrasher (voice) / Emergency Worker 3 (voice) / Glurfsberg Cop 2 (voice) / Yes Man (voice) / Schvizelton Neighbor 3 (voice) / Pokie-McDokie Man / Cabbie Right (voice) / Proprietor 6 (voice) / Zook Goon 1 (voice) / Grandpa (voice) / Flea (voice) / Jeremy (voice) / Boss (voice)

Suzy Eddie Izzard

Snerz (voice)

Jeffrey Wright

McWinkle (voice)

Keith Ferguson

Crony 3 (voice) / Confused Employee (voice) / Guard 1 / Hat Man (voice) / Zook Goon 2 (voice) / Bus Announcer (voice) / Executive (voice) / Patron 1 (voice) / Carnie (voice) / News Anchor (voice) / Additional Biker 2 (voice) / Inventor #2 (voice)